Sugar acids and derivatives
Medchemexpress LLC Integrin alpha V bet 10ug | 10ug
Integrin V beta 5 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 5 Protein Human (HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 5 protein expressed by HEK293 with C-Avi C-His labeled tag Integrin alpha V beta 5 Protein Human (HEK293 His-Avi) has molecular weight of 85-160 kDa
Medchemexpress LLC IL-1RA/IL-1F3 Porci 500ug | 500ug
IL-1RA/IL-1F3 proteins are powerful anti-inflammatory antagonists in the interleukin 1 family specifically targeting the pro-inflammatory cytokines IL1B and IL1A This protein counteracts the inflammatory effects of IL1 playing a critical role in preventing immune dysregulation and preventing uncontrolled systemic inflammation triggered by a variety of innate irritants including pathogens IL-1RA/IL-1F3 Protein Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein expressed by E coli with tag free
Medchemexpress LLC BET-IN-14 | 2243669-93-2 | C30H37N7O2 | 1 MG
BET-IN-14 is an orally active pan BET inhibitor (IC50: 5.35 nM) exhibiting anti-cancer activity. It shows anti-tumor effects against various cancer cell lines, including MM.1S, Ty-82, MV-4-11, and KG-1 cells, with an average IC50 of 174.7 nM after 72 hours. In vivo, BET-IN-14 inhibits tumor growth in MV-4-11 xenograft models.
- Orally active pan BET inhibitor
- Exhibits anti-cancer activity
- Effective against various cancer cell lines (MM.1S, Ty-82, MV-4-11, KG-1)
- Inhibits tumor growth in xenograft models
Medchemexpress LLC 4-Methylumbelliferyl β-D-galactopyranoside | 6160-78-7 | MFCD00036773 | 99.1% | 338.31 | 500 MG
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase. When cleaved, it produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer.
- Fluorescent substrate for β-galactosidase
- Produces a water-soluble blue fluorescent coumarin fluorophore when cleaved
- Detectable using a fluoroenzymeter or fluorometer
- White to off-white solid
- Molecular weight of 338.31
- Purity of 99.06%
- Excitation at 390 nm
- Emission at 480 nm
Medchemexpress LLC Integrin alpha V beta 3 protein | >95.0% | 100UG
Recombinant mouse integrin αVβ3 heterodimer, biotinylated and expressed in HEK293 cells with C-terminal His and Avi tags; supplied for biochemical and cell-based assays including binding studies and immobilization.
- Biotinylated for detection and streptavidin-based immobilization.
- Expressed in mammalian cells to preserve native folding and post-translational modifications.
- His and Avi tags facilitate purification and biotinylation workflows.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Suitable for ELISA, surface plasmon resonance, and receptor binding assays.
- Store at -20°C and freeze aliquots for extended storage.
Cayman Chemical D-GlucuronIc AcId 5g
A metabolite of glucose; a component of proteoglycans; levels are increased in fibroblasts isolated from patients with ISSD or Salla disease
Medchemexpress LLC IL-1RA/IL-1F3 Porci 5ug | 5ug
IL-1RA/IL-1F3 proteins are powerful anti-inflammatory antagonists in the interleukin 1 family specifically targeting the pro-inflammatory cytokines IL1B and IL1A This protein counteracts the inflammatory effects of IL1 playing a critical role in preventing immune dysregulation and preventing uncontrolled systemic inflammation triggered by a variety of innate irritants including pathogens IL-1RA/IL-1F3 Protein Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein expressed by E coli with tag free
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 1 MG
Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity, supporting the healing of ulcerative colitis. It also enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. Additionally, it modulates gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
- Exhibits anti-inflammatory activity
- Supports healing of ulcerative colitis
- Enhances intestinal barrier function
- Modulates gut microbiota
- Increases beneficial bacterial populations
- Suppresses harmful bacterial populations
Medchemexpress LLC Protac BET-binding moiety 2 | 916493-82-8 | 99.8% | 10 MG
Small-molecule BET bromodomain inhibitor intended as the BET-binding ligand component in PROTAC constructs and for biochemical and cell-based research applications. Supplied as a solid or as a 10 mM solution in DMSO, with reported high purity and identifying registry information for compound verification.
- Functions as a BET bromodomain ligand for PROTAC design and target engagement studies.
- Available as solid powder and as a 10 mM solution in DMSO for assay flexibility.
- High reported purity suitable for research use.
- Characterized by CAS 916493-82-8 and molecular weight 444.89 for identification.
- Provided for research use only; not for human or clinical use.
Medchemexpress LLC Tetrahydrouridine dihydrate | 18771-50-1 | MFCD00063468 | 99.8% | 284.26 g/mol | C9H20N2O8 | 10 MG
Tetrahydrouridine dihydrate is the dihydrated form of tetrahydrouridine, a potent competitive inhibitor of cytidine deaminase (CDA). Supplied as a white to off-white solid for research use, it is used to inhibit cytidine deamination, support studies of DNA/RNA synthesis pathways, and sensitize carcinoma cells to cytidine analog chemotherapeutics such as gemcitabine.
- Potent competitive inhibitor of cytidine deaminase (CDA).
- High purity (≈99.8%) suitable for research applications.
- Dihydrate form; molecular weight 284.26 g/mol.
- White to off-white solid, convenient for analytical and biological assays.
- Stable when stored as powder at -20°C (long-term storage).
- Available in small assay sizes for laboratory use.
Medchemexpress LLC Integrin alpha V bet 5ug
Integrin V beta 5 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 8 Protein Human (HEK293 His solution) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 8 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 8 Protein Human (HEK293 His solution) has molecular weight of 187 95 kDa
Medchemexpress LLC Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 100 MG
Sodium zirconium cyclosilicate is an inorganic, microporous zirconium silicate compound used as a selective cation-exchange reagent that binds potassium ions for biomedical and kidney disease research.
- Selectively binds potassium ions for removal in vitro or preclinical studies.
- Inorganic, non-absorbed microporous structure suitable for research applications.
- Available in multiple small-scale sizes for laboratory use.
- Supplied as a solid reagent with specified purity for experimental reproducibility.
Cayman Chemical 13C6-4-NItronIlIn 10mg
An internal standard for the quantification of 4-nitroaniline by GC- or LC-MS