Sugar acids and derivatives
Medchemexpress LLC Heparin sodium salt | 9041-08-1 | 50 MG
Heparin sodium salt (Sodium heparin) is an anticoagulant that reversibly binds to antithrombin III (ATIII), significantly accelerating its inactivation of coagulation enzymes such as thrombin factor IIa and factor Xa. It also notably inhibits exosome-cell interactions. This potent anticoagulant is a complex linear polymer, stabilizing FGF-FR binding and promoting FGFR dimerization.
- Anticoagulant
- Binds reversibly to antithrombin III (ATIII)
- Accelerates ATIII's inactivation of thrombin factor IIa and factor Xa
- Inhibits exosome-cell interactions
- Stabilizes FGF-FR binding and promotes FGFR dimerization
Aobchem (2-Chloro-3-methoxyphenyl)(cyclopropyl)methanone | 95% | C11H11ClO2 | 250mg
(2-Chloro-3-methoxyphenyl)(cyclopropyl)methanone | 95% | C11H11ClO2 | 250mg
Medchemexpress LLC DCP-LA | 28399-31-7 | 98.0% | 308.50 | 25 MG
DCP-LA is a linoleic acid derivative that selectively and directly activates PKCε. It also activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. Additionally, DCP-LA inhibits the activation of caspase-3/-9 and helps protect neurons from oxidative stress-induced apoptosis.
- Selectively and directly activates PKCε
- Activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII)
- Inhibits protein phosphatase-1 (PP-1)
- Stimulates AMPA receptor exocytosis
- Inhibits activation of caspase-3/-9
- Helps protect neurons from oxidative stress-induced apoptosis
- Facilitates hippocampal synaptic transmission
- Exhibits protective effect against ischemic brain damage
eMolecules 21085-72-3 | Acetobromo-alpha-D-glucuronic acid, methyl ester | Apollo Scientific US - Building Blocks | MFCD00061613 | 397.174 | C13H17BrO9 | 95.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 5g | 397994724
Acetobromo-alpha-D-glucuronic acid, methyl ester | Apollo Scientific US - Building Blocks | 21085-72-3 | MFCD00061613 | 397.174 | C13H17BrO9 | 95.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 5g | 397994724
![Alkali Scientific MUP [4 Methylumbelliferyl Phosphate], 250 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661678.jpg-250.jpg)
Alkali Scientific MUP [4 Methylumbelliferyl Phosphate], 250 Mg
Methylumbelliferyl Phosphate (MUP) 250 mg is a fluorogenic substrate used in enzyme assays to measure enzyme activity with high sensitivity. MUP is widely employed for detecting alkaline phosphatase and other enzymes in various biological research applications. The substrate undergoes hydrolysis by enzymes to produce a fluorescent signal, which can be quantitatively analyzed. This makes MUP a powerful tool for studying enzyme kinetics and enzyme inhibition. The 250 mg formulation is ideal for mid-scale experiments and is commonly used in clinical diagnostics, environmental testing, and pharmaceutical research, where precise enzyme activity measurements are essential for analysis.
![eMolecules 21085-72-3 | Acetobromo-?-D-glucuronic acid methyl ester, 98% | ChemScene | MFCD00061613 | 397.174 | C13H17BrO9 | 98.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 15g | 894453228](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000482129.jpg-250.jpg)
eMolecules 21085-72-3 | Acetobromo-?-D-glucuronic acid methyl ester, 98% | ChemScene | MFCD00061613 | 397.174 | C13H17BrO9 | 98.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 15g | 894453228
Acetobromo-?-D-glucuronic acid methyl ester, 98% | ChemScene | 21085-72-3 | MFCD00061613 | 397.174 | C13H17BrO9 | 98.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 15g | 894453228
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 25 MG
Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity, supporting the healing of ulcerative colitis. It enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. Additionally, Glucuronic acid sodium modulates gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
- Exhibits anti-inflammatory activity
- Supports healing of ulcerative colitis
- Enhances intestinal barrier by upregulating tight junction proteins
- Modulates gut microbiota by increasing beneficial bacterial populations
- Suppresses harmful bacterial populations
Medchemexpress LLC UDP-glucuronic acid (trisodium) | 63700-19-6 | 500 MG
UDP-glucuronic acid trisodium (Uridine 5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates found across various biological kingdoms, including mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. In in vitro studies, it has been shown to promote the migration of liver cancer cells (Huh7, SK-Hep1, and SNU449) by inducing the EMT process.
- Critical precursor for essential glycoconjugates.
- Promotes migration of liver cancer cells.
- Induces the epithelial-mesenchymal transition (EMT) process.
- Decreases E-cadherin levels in Huh7 and SNU449 cells.
- Increases vimentin levels in Huh7 and SNU449 cells.
![Medchemexpress LLC (S,E)-N-(4-(2-((6-(2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f]triazolo[4,3-a]diazepin-6-yl)acetamido)hexyl)amino)-2-oxoethoxy)benzyl)-2-cyano-3-(naphthalen-2-yl)acrylamide | 98.1% | 867.46 | C48H47ClN8O4S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000288277.png-250.jpg)
Medchemexpress LLC (S,E)-N-(4-(2-((6-(2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f]triazolo[4,3-a]diazepin-6-yl)acetamido)hexyl)amino)-2-oxoethoxy)benzyl)-2-cyano-3-(naphthalen-2-yl)acrylamide | 98.1% | 867.46 | C48H47ClN8O4S | 10 MG
PROTAC BET Degrader-12 is a proteolysis targeting chimera (PROTAC) designed to selectively degrade bromodomain and extra-terminal (BET) family proteins such as BRD3 and BRD4. Supplied as a research reagent in small-mass packs, it is intended for use in targeted protein degradation and epigenetics studies.
- Selective BET protein degrader targeting BRD3 and BRD4.
- Purity 98.1% by HPLC.
- Molecular formula C48H47ClN8O4S; molecular weight 867.46.
- Available in small-mass packs (e.g., 10 mg) for research use.
- Storage: 4°C, protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or diagnostic use.
Medchemexpress LLC D-Thyroxine | 51-49-0 | 98.0% | C15H11I4NO4 | 25 MG
D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. It can inhibit goiter, promote metamorphosis of tadpoles, and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia. This product is intended for research applications only.
- Orally active thyroid hormone
- Inhibits the secretion of TSH
- Can inhibit goiter
- Promotes metamorphosis of tadpoles
- Influences cholesterol metabolism
- Used for the study of hypercholesterolemia
Medchemexpress LLC [3,3'-Bipyridine]-5-carboxamide, 6'-chloro-N-methyl-5'-[(phenylsulfonyl)amino]- | 2377604-81-2 | 523747 | C18H15ClN4O3S | 25 MG
CHMFL-PI4K-127 is an orally active, potent, and highly selective PfPI4K (Plasmodium falciparum PI4K kinase) inhibitor with an IC50 of 0.9 nM. It demonstrates potent activity against 3D7 Plasmodium falciparum, with an EC50 of 25.1 nM, and exhibits antimalaria efficacy.
- Potent and selective PfPI4K inhibitor.
- Exhibits antimalaria efficacy.
- Orally active compound.